abstract：:In the present study we examined the association between baseline alcohol consumption and 10-year mortality in subjects with normal and abnormal glucose levels (diabetes, impaired fasting glucose (IFG) or impaired glucose tolerance (IGT)). Furthermore, we assessed the 6-year cumulative incidence of diabetes in categor...

journal_title：Diabetes research and clinical practice

authors： de Vegt F,Dekker JM,Groeneveld WJ,Nijpels G,Stehouwer CD,Bouter LM,Heine RJ

更新日期：2002-07-01 00:00:00

abstract：:This cross-sectional study compared serum lipoprotein (a) [Lp(a)] concentrations in type 1 and type 2 diabetic subjects and examined the determinants of Lp(a) concentrations in both types of diabetes. Serum Lp(a) was measured in 26 type 1 and 107 type 2 diabetic patients and 126 non-diabetic controls. HbA(1c), fasting...

journal_title：Diabetes research and clinical practice

authors： Nawawi HM,Muhajir M,Kian YC,Mohamud WN,Yusoff K,Khalid BA

更新日期：2002-06-01 00:00:00

abstract：:This study examined the prevalence of retinopathy in 2131 patients with type 2 diabetes attending a Beijing hospital for the first time. The median age of patients was 58 years (IQR 50-65). The overall prevalence of retinopathy was 27.3% (95% CI: 25.4-29.2) and for proliferative retinopathy 7.8% (95% CI: 6.7-8.9). Whe...

journal_title：Diabetes research and clinical practice

authors： Liu DP,Molyneaux L,Chua E,Wang YZ,Wu CR,Jing H,Hu LN,Liu YJ,Xu ZR,Yue DK

更新日期：2002-05-01 00:00:00

abstract：UNLABELLED:Type 1 diabetes in Sardinia is very common in children, and we hypothesized that Latent Autoimmune Diabetes of Adult (LADA) might constitute a significant proportion of diabetes in adult Sardinian subjects. Since Type 2 diabetes is a familial disorder, we tested this hypothesis by investigating the prevalenc...

journal_title：Diabetes research and clinical practice

authors： Maioli M,Tonolo G,Bekris L,Cirillo R,Schranz D,Cossu E,Ciccarese M,Lernmark A,Study Group for the Genetics of Diabetes in Sardina (SGGDS).

更新日期：2002-04-01 00:00:00

abstract：:We measured the cell-mediated immune response to GAD and bovine beta-casein in 38 type 1 and 37 type 2 diabetic patients who visited diabetic clinics or who were hospitalized in Bangkok, Thailand, and in 43 normal controls, by using a lymphoproliferation assay. Positive results against GAD were found in 29/38 (76.3%) ...

journal_title：Diabetes research and clinical practice

authors： Banchuin N,Boonyasrisawat W,Vannasaeng S,Dharakul T,Yenchitsomanus PT,Deerochanawong C,Ploybutr S,Sriussadaporn S,Pasurakul T

更新日期：2002-03-01 00:00:00

abstract：:In this study, we examined the relationships of the fat distribution with the clinical parameters, microangiopathy, and coagulation disorders in Japanese diabetic patients, distinguishing between males and females. To investigate these relationships, the clinical parameters of the patients were compared with the total...

journal_title：Diabetes research and clinical practice

authors： Asakawa H,Tokunaga K,Kawakami F

更新日期：2002-02-01 00:00:00

abstract：:A low-carbohydrate/high-fat evening meal impaired the glucose tolerance of healthy subjects to almost the same extent as the impairment caused by overnight fasting. This suggests that the decreased component (carbohydrate) is more relevant than the increased component (fat) to the impairment of glucose tolerance by a ...

journal_title：Diabetes research and clinical practice

authors： Wang Y,Kaneko T,Wang PY,Sato A

更新日期：2002-01-01 00:00:00

abstract：AIMS:To compare the effect of a fixed combination of an oestrogen (17-beta oestradiol) with a cyclical progestagen (norethisterone) on glycaemic control, plasma lipoproteins and haemostatic factors in women with Type 2 diabetes. METHODS:Oral and transdermal hormone replacement therapy (HRT) were compared to no HRT tre...

journal_title：Diabetes research and clinical practice

authors： Darko DA,Dornhorst A,Kennedy G,Mandeno RC,Seed M

更新日期：2001-12-01 00:00:00

abstract：:A hypothesis that mitochondrial genome itself is the thrifty genome has been advanced, as both its mutation, or quality, and amount in the peripheral blood, or quantity, are found to have close relationship to diabetes mellitus, or more specifically insulin resistance. Mere presence of relationship, however, does not ...

journal_title：Diabetes research and clinical practice

authors： Lee HK

更新日期：2001-12-01 00:00:00

abstract：:The aim of this study was to provide an overview of diabetes management and complication status in Taiwan. A cohort of 2446 patients (from 25 diabetic centers) with more than 12 months of diabetes management participated and data were collected by interviews and reviewing the medical records. Overall, 97% were diagnos...

journal_title：Diabetes research and clinical practice

authors： Chuang LM,Tsai ST,Huang BY,Tai TY,DIABCARE (Taiwan) Study Group.

更新日期：2001-11-01 00:00:00

abstract：:Hormone replacement therapy (HRT) is prescribed less frequently to women with diabetes. In this article, we review the effects of HRT on glucose metabolism and plasma lipids in women with type 2 diabetes. Current evidence is reassuring about the effects of HRT in women with diabetes, although as in all women, HRT shou...

journal_title：Diabetes research and clinical practice

authors： Palin SL,Kumar S,Sturdee DW,Barnett AH

更新日期：2001-11-01 00:00:00

abstract：:We investigated gender differences in the relationships between the Trp64Arg variant of the beta(3)-adrenergic receptor (AR) gene in obesity and insulin resistance in nondiabetic subjects. In 476 nondiabetic Japanese-Americans (M/F=204/272), the Trp64Arg variant of the beta(3)-AR gene was examined. The presence or abs...

journal_title：Diabetes research and clinical practice

authors： Kawamura T,Egusa G,Fujikawa R,Okubo M

更新日期：2001-10-01 00:00:00

abstract：:Glomerular hyperfiltration plays a pathogenic role in the early stages of diabetic nephropathy. Experimental studies in laboratory animals suggest that nitric oxide (NO) might be involved in the pathogenesis of glomerular hyperfiltration. We performed a cross-sectional study to determine the relationship between diabe...

journal_title：Diabetes research and clinical practice

authors： Hiragushi K,Sugimoto H,Shikata K,Yamashita T,Miyatake N,Shikata Y,Wada J,Kumagai I,Fukushima M,Makino H

更新日期：2001-09-01 00:00:00

abstract：:The aim was to establish mortality rates in a cohort of subjects with type 2 diabetes mellitus over 10 years in Canterbury, New Zealand (NZ) and to determine baseline prognostic factors. Subjects (447) with type 2 diabetes (208 male, 239 female; age range 30-82 years, median 62 years; of predominantly European origin)...

journal_title：Diabetes research and clinical practice

authors： Florkowski CM,Scott RS,Coope PA,Moir CL

更新日期：2001-08-01 00:00:00

abstract：:Activity of the lower leg muscles in response to an unexpected disturbance to upright standing was studied in diabetic patients and non-diabetic matched controls. The diabetic individuals were classified into two groups: diabetic patients with normal cutaneous sensitivity in the foot (n=27) and patients with cutaneous...

journal_title：Diabetes research and clinical practice

authors： Simmons RW,Richardson C

更新日期：2001-07-01 00:00:00

abstract：:We ascertained frequencies of autoantibodies to a suite of islet cell antigens including ICA512/IA2 and SOX13 in Asian Indians with Type 1 diabetes and in other forms of diabetes. Autoantibodies to ICA512/IA2 and SOX13 were tested by radioimmunoprecipitation assay, and results were amalgamated with previous data on an...

journal_title：Diabetes research and clinical practice

authors： Fida S,Myers M,Mackay IR,Zimmet PZ,Mohan V,Deepa R,Rowley MJ

更新日期：2001-06-01 00:00:00

abstract：:Insulin resistance is known as an important risk factor for coronary artery disease (CAD). However, CAD-related mortality in Japanese type 2 diabetics is lower than in Caucasians. To investigate whether insulin resistance is related to CAD in Japanese type 2 diabetics, we measured insulin sensitivity and several coron...

journal_title：Diabetes research and clinical practice

authors： Matsumoto K,Kizaki Y,Fukae S,Tomihira M,Sera Y,Ueki Y,Tominaga T,Miyake S

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVES:To compare cardiovascular risk factors and LDL particle size in well-controlled Type 2 diabetes mellitus and normal subjects. METHODS:Ninety-three Type 2 diabetic males and 186 age-matched, male controls were studied. Glycaemic control was stable for at least 3 months prior to recruitment. None were on insu...

journal_title：Diabetes research and clinical practice

authors： Tan CE,Chew LS,Chio LF,Tai ES,Lim HS,Lim SC,Jayakumar L,Eng HK,Packard CJ

更新日期：2001-02-01 00:00:00

abstract：:A 67-year-old woman with diabetes mellitus was hospitalized due to a throbbing headache. She appeared neurologically normal, except for meningeal irritation. The cerebrospinal fluid pressure was high. There was increased fluid protein without an increased cell count. Brain CT scan showed no abnormality, however, brain...

journal_title：Diabetes research and clinical practice

authors： Nagai T,Tomizawa T,Tonooka N,Mita Y,Misumi S,Mori M

更新日期：2001-01-01 00:00:00

abstract：:Human NPH U100 (100 IU/ml), given once daily, is often absorbed too fast to cover the basal insulin demand throughout 24 h. The aim of the present study was to examine whether the absorption of human insulin suspensions would be delayed by increasing the insulin concentration from U100 to U500. In each experiment 10 I...

journal_title：Diabetes research and clinical practice

authors： Jørgensen KH,Hansen AK,Buschard K

更新日期：2000-12-01 00:00:00

abstract：:A method is described for estimating the life-expectancy of cohorts of type 2 diabetic patients, based on computer simulation from a parametric model. The method can be used where non-parametric methods, such as the Kaplan-Meier estimate, fail due to lack of the data. The simulation algorithm combines observed and mod...

journal_title：Diabetes research and clinical practice

authors： Stevens R,Adler A,Gray A,Briggs A,Holman R

更新日期：2000-11-01 00:00:00

abstract：:Population studies all over the world have clearly showed that the prevalence of Type 2 diabetes mellitus (DM) is escalating at phenomenal scale and very likely we are heading towards epidemic proportions. In 1985, the estimated population of diabetic individuals in the world was 30 million but by 1995 this figure soa...

journal_title：Diabetes research and clinical practice

authors： Zaini A

更新日期：2000-10-01 00:00:00

abstract：:The relations between blood glucose control (HbA(1c)), smoking, and health-related diabetes locus of control beliefs were studied in a consecutive adult sample of 187 patients with Type 1 diabetes who were free of diabetes complications. Those who were smokers (n=32) had poorer HbA(1c) values than non-smokers [7.5+/-1...

journal_title：Diabetes research and clinical practice

authors： Stenström U,Andersson P

更新日期：2000-10-01 00:00:00

abstract：:Serum total sialic acid is a marker of the acute phase response. Elevated levels have also been associated with cardiovascular disease in the general Caucasian population and especially in Type 2 diabetic subjects. The purpose of this study was to estimate serum total sialic acid concentrations among Kuwaiti Type 2 di...

journal_title：Diabetes research and clinical practice

authors： Abdella N,Akanji AO,Mojiminiyi OA,Al Assoussi A,Moussa M

更新日期：2000-09-01 00:00:00

abstract：:We report a case of chronic hepatitis C presenting insulin-dependent diabetes mellitus (IDDM) associated with various autoantibodies including possible anti-insulin receptor antibody (AIRA) during interferon (IFN) therapy. A 57-year-old man having chronic hepatitis C virus (HCV) infection with chronic thyroiditis rece...

journal_title：Diabetes research and clinical practice

authors： Uto H,Matsuoka H,Murata M,Okamoto T,Miyata Y,Hori T,Ido A,Hirono S,Hayashi K,Tsubouchi H

更新日期：2000-08-01 00:00:00

abstract：:Study was made on the necessity and importance of the oral glucose tolerance test (OGTT) for diagnosing diabetes mellitus based on prevalence and incidence of diabetic retinopathy. Subjects were 12208 persons undergoing OGTT between 1965 and 1997. The prevalence of retinopathy was significantly elevated with FPG>/=126...

journal_title：Diabetes research and clinical practice

authors： Ito C,Maeda R,Ishida S,Harada H,Inoue N,Sasaki H

更新日期：2000-08-01 00:00:00

abstract：:To critically evaluate the relative importance of coagulation abnormalities over other clinical variables for micro- and macrovascular diabetic complications, prothrombin fragment (F1+2), thrombin-antithrombin III complex (TAT), fibrin degradation product d-dimer, and alpha2 plasmin inhibitor complex were determined i...

journal_title：Diabetes research and clinical practice

authors： Yamada T,Sato A,Nishimori T,Mitsuhashi T,Terao A,Sagai H,Komatsu M,Aizawa T,Hashizume K

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:This study was conducted to assess the adverse effects of diabetic nephropathy on cardiovascular autonomic neuropathy (CAN) in South Indian Type 2 diabetic patients. METHODS:Comparison was made between Type 2 diabetic patients with nephropathy (group 1, n=25), Type 2 diabetic patients without nephropathy (gr...

journal_title：Diabetes research and clinical practice

authors： Viswanathan V,Prasad D,Chamukuttan S,Ramachandran A

更新日期：2000-06-01 00:00:00

abstract：:Previously, we have reported that the lipoprotein fraction containing intermediate density lipoprotein (IDL) and low density lipoprotein (LDL) isolated from diabetics stimulates an atherogenic cytokine in cultured endothelial cells. To study which lipoprotein fraction isolated from diabetics can modulate the gene expr...

journal_title：Diabetes research and clinical practice

authors： Maeno Y,Kashiwagi A,Nishio Y,Takahara N,Kikkawa R

更新日期：2000-05-01 00:00:00

abstract：:To determine the prevalence of micro vascular and macro vascular complications in Asian Indian Type 1 diabetic subjects. There has been no major report on the prevalence of vascular complications in Type 1 diabetic patients in India. This study was done in Type 1 diabetic patients, aged < or =20 years at diagnosis of ...

journal_title：Diabetes research and clinical practice

authors： Ramachandran A,Snehalatha C,Sasikala R,Satyavani K,Vijay V

更新日期：2000-04-01 00:00:00

abstract：:GM and KM immunoglobulin allotypes, which are the markers, respectively, of the constant parts of the heavy and the light chains of the IgG1, IgG2 and IgG3 subclasses, have been analysed in diabetic mellitus patients and controls living in New Caledonia. We tested 40 Europeans, 256 Melanesians and 44 Polynesians, as w...

journal_title：Diabetes research and clinical practice

authors： Dugoujon JM,Guitard E,Sénégas MT,Roth MP,Sanchez A,Barny S,Simon D,Papoz L

更新日期：2000-03-01 00:00:00

abstract：:In recent years, out-patient protocols have mainly displaced historical obstetric management of diabetic pregnancy. The impact of the change from centralized in-patient to decentralized out-patient treatment on glycaemic control and its effects on the outcome of newborns in diabetic pregnancies was therefore studied u...

journal_title：Diabetes research and clinical practice

authors： Vääräsmäki M,Hartikainen AL,Anttila M,Pirttiaho H

更新日期：2000-02-01 00:00:00

abstract：:We evaluated the association of Chlamydia pneumoniae (CP) infection with progression of diabetic nephropathy. Type 2 diabetic patients (60) were divided into two groups, those with incipient nephropathy and those with advanced nephropathy, based on the severity of diffuse glomerular lesions using Gellman's criteria. T...

journal_title：Diabetes research and clinical practice

authors： Kanauchi M,Kawano T,Dohi K

更新日期：2000-01-01 00:00:00

abstract：:The presence of injection related anxiety and phobia may influence compliance, glycaemic control and quality of life in patients with insulin-treated diabetes. Unselected consecutive, insulin-treated patients attending a diabetes clinic for follow-up, completed a standardised questionnaire providing an injection anxie...

journal_title：Diabetes research and clinical practice

authors： Zambanini A,Newson RB,Maisey M,Feher MD

更新日期：1999-12-01 00:00:00

abstract：:In controlled trials intensified diabetes therapy including multiple insulin injection regimes has been shown to improve glycaemic and microvascular disease outcomes in insulin dependent diabetes but this is not clear in routine outpatient practice. We undertook a pragmatic cross sectional study of 200 patients with T...

journal_title：Diabetes research and clinical practice

authors： Pawar BK,Walford S,Singh BM

更新日期：1999-11-01 00:00:00

abstract：:The increased susceptibility to atherosclerosis of diabetic individuals, may result from diabetes-associated modification in plasma low density lipoproteins (LDL) which enhance their interaction with arterial extracellular matrix proteoglycans. Using a nonhuman primate model for human diabetes, studies were conducted ...

journal_title：Diabetes research and clinical practice

authors： Edwards IJ,Wagner JD,Litwak KN,Rudel LL,Cefalu WT

更新日期：1999-10-01 00:00:00

abstract：:Diabetes mellitus is associated with increased frequency, severity and more rapid progression of cardiovascular diseases. Metabolic perturbations from hyperglycemia result in disturbed endothelium-dependent relaxation, activation of coagulation pathways, depressed fibrinolysis, and other abnormalities in vascular home...

journal_title：Diabetes research and clinical practice

authors： Papadaki M,Eskin SG,Ruef J,Runge MS,McIntire LV

更新日期：1999-09-01 00:00:00

abstract：:Hyperglycemia causes vascular complications of diabetes possible by the activation of protein kinase C (PKC). We have provided substantial evidence that activation of PKC can lead to a whole host of vascular dysfunction in diabetes. The activation of PKC induced by hyperglycemia appears to be due to an increase in dia...

journal_title：Diabetes research and clinical practice

authors： Bursell SE,King GL

更新日期：1999-09-01 00:00:00

abstract：:Aldose reductase (AR) protein was measured in peripheral mononuclear cells (PMCs) from 55 patients with type 2 diabetes by a two-site ELISA using anti-human AR monoclonal antibody. AR levels did not correlate with age, duration of diabetes, and HbAlc. Furthermore, no significant differences were found in AR levels bet...

journal_title：Diabetes research and clinical practice

authors： Hasegawa G,Obayashi H,Kitamura A,Hashimoto M,Shigeta H,Nakamura N,Kondo M,Nishimura CY

更新日期：1999-08-01 00:00:00

abstract：:Use of a real-time bedside glucose monitor was analyzed during the course of management of diabetic ketoacidosis (DKA) in children. Simultaneous determinations of blood glucose were obtained, using three methods: bedside glucose meter (One Touch II), laboratory glucose analyzer (YSI 2300 STAT), and a real-time bedside...

journal_title：Diabetes research and clinical practice

authors： Coss-Bu JA,Jefferson LS,Stone-McCord S,Ou CN,Watrin C,Sachdeva R,Copeland KC

更新日期：1999-06-01 00:00:00